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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
23.33
Human Site:
Y114
Identified Species:
36.67
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
Y114
R
P
R
P
D
F
F
Y
R
C
F
P
D
G
V
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
K67
G
V
F
T
N
T
I
K
L
I
V
G
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
L173
Q
A
C
L
A
A
S
L
A
L
A
L
N
G
V
Dog
Lupus familis
XP_535038
333
36609
Y176
R
P
R
P
D
F
F
Y
R
C
F
P
D
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
Y114
R
P
R
P
D
F
F
Y
R
C
F
P
D
G
V
Rat
Rattus norvegicus
O08564
282
31978
S112
F
L
F
G
A
S
A
S
Q
S
L
T
D
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
Y120
R
P
R
P
D
F
F
Y
R
C
F
P
D
G
V
Chicken
Gallus gallus
XP_426544
322
36285
Y165
R
P
R
P
D
F
F
Y
R
C
F
P
D
G
V
Frog
Xenopus laevis
Q6GQ62
226
25153
V70
T
N
T
V
K
L
I
V
G
R
P
R
P
D
F
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
Q121
R
P
R
P
D
Y
Y
Q
R
C
F
P
D
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
I111
I
T
D
I
I
K
L
I
V
G
R
P
R
P
D
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
C165
C
K
L
A
N
D
T
C
V
T
G
D
S
H
R
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
Y101
K
P
R
P
D
F
F
Y
R
C
F
P
N
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
F133
P
D
F
F
W
R
C
F
P
D
G
I
G
I
F
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
D130
R
L
R
P
D
F
L
D
R
C
Q
P
V
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
0
13.3
100
N.A.
100
6.6
N.A.
100
100
0
73.3
N.A.
N.A.
6.6
0
86.6
P-Site Similarity:
100
6.6
26.6
100
N.A.
100
13.3
N.A.
100
100
0
86.6
N.A.
N.A.
6.6
6.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
14
7
7
0
7
0
7
0
0
0
7
% A
% Cys:
7
0
7
0
0
0
7
7
0
54
0
0
0
0
0
% C
% Asp:
0
7
7
0
54
7
0
7
0
7
0
7
47
7
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
7
0
20
7
0
47
40
7
0
0
47
0
0
0
14
% F
% Gly:
7
0
0
7
0
0
0
0
7
7
14
7
7
54
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
7
7
0
14
7
0
7
0
7
0
14
0
% I
% Lys:
7
7
0
0
7
7
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
14
7
7
0
7
14
7
7
7
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
14
0
0
0
0
0
0
0
14
0
0
% N
% Pro:
7
47
0
54
0
0
0
0
7
0
7
60
7
14
0
% P
% Gln:
7
0
0
0
0
0
0
7
7
0
7
0
0
0
7
% Q
% Arg:
47
0
54
0
0
7
0
0
54
7
7
7
14
0
14
% R
% Ser:
0
0
0
0
0
7
7
7
0
7
0
0
7
0
0
% S
% Thr:
7
7
7
7
0
7
7
0
0
7
0
7
0
0
0
% T
% Val:
0
7
0
7
0
0
0
7
14
0
7
0
7
0
47
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _